GBL date drug
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GBL date drug
introduction:
Gamma-butyrolactone (GBL), a chemical used in industry, is a precursor to and illegal alternative for gamma-hydroxybutyric acid (GHB).
Because GBL and 1,4-butadiene (BD) share structural similarities with GHB,
there is evidence that these compounds are transformed to GHB when taken orally.
Schedule I depressants include GHB. Teens and young adults began abusing GHB in dance clubs and “raves”
in the 1990s, and gained notoriety as a date rape drug.
gbl can also be defined as
Gamma-Butyrolactone, or GBL, is a colorless, water-soluble liquid that is hygroscopic and has a faint distinctive odor.
The simplest 4-carbon lactone is this one.
It is primarily employed as a chemical building block in the synthesis of other substances, such as methyl-2-pyrrolidone.
GBL is used as a recreational CNS depressant in humans, where it functions as a prodrug for gamma-hydroxybutyric acid
(GHB) and has effects akin to those of barbiturates.
Occurrence
Extracts from samples of unadulterated wines have been confirmed to contain GBL.
According to this research, GBL is a naturally occurring substance that can be found in some wines and possibly other items.
Using a straightforward extraction method and GC/MS measurement, the concentration of about 5 g/mL was easily observed.
GBL can be detected in cheese flavorings, however the final food product normally contains only 0.0002% GBL.
How is GBL made? or What is GBL made out of?
Production and Synthesis
Industrial production of -butyrolactone involves dehydrogenating 1,4-butanediol at temperatures between 180 and 300 °C at atmospheric pressure while using a copper catalyst.
This method has a 95% yield on average. An extraction using the liquid-gas phase is used for purification.
It can also be made in the lab by oxidizing tetrahydrofuran (THF), perhaps with aqueous sodium bromate.
An alternate pathway leaves GABA and travels through a diazonium intermediate.
Reactions
GBL is hydrolyzed into sodium gamma-hydroxybutyrate, the sodium salt of gamma-hydroxybutyric acid, when it is exposed to basic
conditions as a lactone. An equilibrium between lactone and acid forms can be found in acidic water.
The polymer poly(4-hydroxybutyrate) and the dimer 1,6-Dioxecane-2,7-dione may then be created from these molecules.
When GBL is exposed to a non-nucleophilic base, such as lithium diisopropylamide, the alpha carbon atom deprotonates to the carbonyl.
This method allows for the production of polyester from the related molecule caprolactone.
Polymerization
Poly Butyrolactone is produced when butyrolactone undergoes ring-opening polymerization.
The product undergoes heat cracking to return to the monomer.
It is asserted that poly(GBL) and the commercial biomaterial poly(4-hydroxybutyrate), or P4HB, are competitive.
Even though both materials are generated from nature, it is further asserted that poly(GBL) is less expensive to produce than P4HB.
GBL date drug
Gamma-hydroxybutyrate (GHB), though occasionally referred to as a date rape drug, is really used recreationally and consensually. Although it is frequently used by gay men during chemsex, which is when chemicals are used to increase sex between two or more people, it is also a common party drug among heterosexuals.Jan 6, 2020
Gamma-hydroxybutyrate (GHB), though occasionally referred to as a date rape drug, is really used recreationally and consensually.
Although it is frequently used by gay men during chemsex, which is when chemicals are used to increase sex between two or more people, it is also a common party drug among heterosexuals.
However, rapists employ GHB as a weapon; according to a recent survey, more than 25% of individuals surveyed had been sexually assaulted while they were unconscious.
